guide
HESI A2 Vocabulary study guide
How a word's meaning is decided by its sentence: the five context clues, the prefix-root-suffix system with a combining vowel, tables of the parts health care actually uses, irregular plurals, confusable pairs, and the general and health-care word lists this topic draws on.
What this topic actually asks of you
Vocabulary on this exam asks what a word means, and the work splits in two directions: reading a word from its context, and taking a long medical word apart into the pieces a health-care vocabulary is built from.
Elsevier lists vocabulary among the areas the HESI A2 covers. The publisher releases no national content specification — no item count, no clock, no cut score — so nothing on this page mirrors an official weighting, and nothing here claims to. What this page offers is a word-part system and a word list: the prefixes, roots and suffixes that build terms, and a plain-English list of the general and health-care words a passage is likely to use, each with its own example sentence.
The word parts follow the US National Library of Medicine's consumer guide to medical words; the definitions are standard meanings written for this course, with no dictionary text copied, and every example sentence is ours.
The nine ideas this page teaches
- Context clues — the six ways a sentence tells you what a word means.
- How a medical word is built — prefix, then root, then suffix, with a combining vowel when the suffix starts with a consonant.
- Prefixes of position, size and speed — the largest group, and the one that changes a word's direction.
- Roots — the body part or the substance the word is about.
- Suffixes — what is being done, and whether the word names a condition, a procedure or a specialist.
- Plurals of medical words — the endings that do not simply add an s.
- Confusable pairs — affect and effect, accept and except, and the rest of the pairs that look alike.
- Academic and health-care words — the general vocabulary of a passage about care, risk and outcome.
- Deriving an unknown word — what to do when a term is not on this page.
Context clues: six ways a sentence tells you
| Clue | What the sentence does | Example |
|---|---|---|
| Context clue: definition | a direct statement of the meaning, often in an appositive after a comma or a dash | "The patient was afebrile — no fever at all — for three days." |
| Context clue: restatement | a rewording in ordinary words nearby, set off by commas or a dash, that adds no new information | "The wound was superficial, involving only the top layer of skin." |
| Context clue: contrast | supplies the opposite, so the word must be its reverse | "The first dose was benign in its effects, unlike the second, which caused a rash." |
| Context clue: example | lists instances, and the word names the category | "Vital signs such as pulse, blood pressure and temperature were recorded hourly." |
| Context clue: cause and effect | the word's consequence is stated | "Because the dressing was occlusive, it sealed the air out and the wound stayed moist." |
| Context clue: general sense | the sentence's tone and subject narrow the meaning | "The second reader would concur with the opinion, so the plan did not change." |
The test for a context answer is a substitution: put your meaning back into the sentence and read it again. If the sentence still says something a nurse would say, the meaning fits. If it says something odd, the sense is wrong even when the word's dictionary meaning is right.
How a medical word is built
A medical term is assembled in a fixed order, and the order is the meaning.
prefix + root + suffix — as in bradycardia: brady- (slow) + card (heart) + -ia (condition), so a slow heart rate.
| Piece | What it contributes | Where it sits | Example |
|---|---|---|---|
| prefix | position, number, size, speed, or a negation | at the front | tachy- in tachycardia, a fast heart rate |
| root | the body part or substance the word is about | in the middle | gastr- in gastritis, inflammation of the stomach |
| combining vowel | usually o, joining a root to a suffix that starts with a consonant | between root and suffix | o in gastroscopy, so the parts do not collide |
| suffix | the condition, procedure, or kind of specialist | at the end | -itis in gastritis, meaning inflammation |
Three rules make the system usable.
- Read a long word from the suffix back to the prefix. The suffix says what kind of thing the word is, the root says where, and the prefix says how.
- Keep the combining vowel only when the suffix begins with a consonant. gastr-o-scopy takes the o because -scopy starts with a consonant; gastr-itis drops it because -itis starts with a vowel.
- Do not read a prefix as a word of its own. -ia at the end of bradycardia is the suffix that names a condition, not the prefix a- that means "without". The same letters, in different positions, are different pieces.
Prefixes: position, size, speed, number, negation
Learn the prefixes by what they do to a word's direction, not as a list of letters. Each one below is a piece of a word you will meet in a health-care passage.
Position
| Prefix | Meaning | Word, and what it means |
|---|---|---|
| ante- | before | antepartum — the period before birth |
| pre- | before | preoperative — before a procedure |
| post- | after | postoperative — after a procedure |
| peri- | around | pericardium — the sac around the heart |
| circum- | around | circumcision — a cutting around |
| sub- | under, below | subcutaneous — under the skin |
| infra- | below | infrared — below red on the spectrum |
| supra- | above | suprapubic — above the pubic bone |
| epi- | on, over | epidermis — the layer over the dermis |
| endo- | within | endocrine — secreting within the body |
| intra- | inside | intravenous — inside a vein |
| inter- | between | intercostal — between the ribs |
| extra- | outside | extracellular — outside the cell |
| trans- | across, through | transdermal — through the skin |
| retro- | backward, behind | retroperitoneal — behind the peritoneum |
| ab- | away from | abduction — movement away from the midline |
| ad- | toward | adduction — movement toward the midline |
Size, speed and amount
| Prefix | Meaning | Word, and what it means |
|---|---|---|
| brady- | slow | bradycardia — a slow heart rate |
| tachy- | fast | tachypnea — fast breathing |
| macro- | large | macrophage — a large cell that engulfs debris |
| micro- | small | microcyte — a small red blood cell |
| mega- | very large | megacolon — an abnormally wide colon |
| hyper- | above normal | hypertension — high blood pressure |
| hypo- | below normal | hypotension — low blood pressure |
| oligo- | few, scanty | oliguria — scanty urine output |
| poly- | many, much | polyuria — excessive urine output |
| eu- | normal, good | eupnea — normal breathing |
| neo- | new | neonate — a newborn |
Number
| Prefix | Meaning | Word, and what it means |
|---|---|---|
| mono-, uni- | one | mononucleosis, unilateral — one side |
| bi-, di- | two | bilateral — both sides |
| tri- | three | tricuspid — a valve with three flaps |
| quadri- | four | quadriplegia — loss of function in all four limbs |
| hemi- | half | hemiplegia — loss of function on one side |
| semi- | half | semicircular — half a circle, as in the ear's canals |
Negation and absence
| Prefix | Meaning | Word, and what it means |
|---|---|---|
| a-, an- | without | afebrile — without fever; anemia — without sufficient blood |
| anti- | against | antibiotic — against bacteria |
| contra- | against | contraindication — a reason against a treatment |
| de- | down, away from | dehydration — loss of water |
| dis- | apart, not | dislocation — displacement of a joint |
| mal- | bad, abnormal | malnutrition — poor nutrition |
| dys- | difficult, abnormal | dyspnea — difficult breathing |
Two prefixes are worth a warning because they look like ordinary words. Hyper- and hypo- differ by one letter and mean opposite things — a hyperglycemic patient is high, a hypoglycemic patient is low, and confusing them is a clinical error, not a vocabulary slip. Dys- means difficult or abnormal, not absent: dysuria is painful urination, anuria is none.
Roots: the body part inside the word
| Root | Means | Word, and what it means |
|---|---|---|
| cardi- | heart | cardiology — the study of the heart |
| pulmon-, pneum- | lung, air | pulmonary — relating to the lungs; pneumonia — an infection of the lung |
| gastr- | stomach | gastrectomy — removal of the stomach |
| hepat- | liver | hepatomegaly — an enlarged liver |
| nephr- | kidney | nephritis — inflammation of a kidney |
| ren- | kidney | renal — relating to the kidney |
| cyst- | bladder, sac | cystoscopy — viewing inside the bladder |
| enter- | intestine | enteritis — inflammation of the intestine |
| col-, colon- | colon | colostomy — an opening into the colon |
| arthr- | joint | arthritis — inflammation of a joint |
| oste- | bone | osteoporosis — bone that has thinned and weakened |
| my-, myo- | muscle | myalgia — muscle pain |
| derm-, dermat- | skin | dermatitis — inflammation of the skin |
| neur- | nerve | neurology — the study of the nervous system |
| encephal- | brain | encephalitis — inflammation of the brain |
| cerebr- | brain | cerebral — relating to the cerebrum |
| hem-, hemat- | blood | hematocrit — the proportion of blood that is red cells |
| vas-, vascul- | vessel | vascular — relating to blood vessels |
| therm- | heat | thermometer — an instrument for measuring heat |
| glyc- | sugar | glycemia — the sugar level in the blood |
| lip- | fat | lipids — fats and fat-like substances |
| cutane- | skin | cutaneous — relating to the skin |
| cost- | rib | intercostal — between the ribs |
| thorac- | chest | thoracic — relating to the chest |
| abdomin- | abdomen | abdominal — relating to the abdomen |
| hist- | tissue | histology — the study of tissue |
Roots come in two spellings more often than the table suggests, and both spellings mean the same thing: nephr- and ren- are both kidney, pneum- and pulmon- are both lung, encephal- and cerebr- are both brain. Either spelling in a word tells you the organ; the rest of the word tells you what is happening to it.
Suffixes: what is being done, and to what kind of word
The suffix tells you what kind of thing the word is — a condition, an inflammation, a procedure, a specialist, or a record. Read it first.
Conditions and processes
| Suffix | Means | Word, and what it means |
|---|---|---|
| -itis | inflammation | gastritis — inflammation of the stomach |
| -osis | a condition, often abnormal | osteoporosis — a condition of thinned bone |
| -iasis | a condition, often caused by something | cholelithiasis — the presence of gallstones |
| -pathy | disease | neuropathy — disease of a nerve |
| -emia | a condition of the blood | anemia — a shortage of red cells or hemoglobin |
| -uria | a condition of the urine | hematuria — blood in the urine |
| -oma | a tumor or swelling | hematoma — a swelling of clotted blood |
| -megaly | enlargement | cardiomegaly — an enlarged heart |
| -plegia | paralysis | paraplegia — loss of function in the lower limbs |
| -pnea | breathing | dyspnea — difficult breathing |
| -rrhea | flow, discharge | diarrhea — a flow of loose stool |
| -spasm | an involuntary contraction | bronchospasm — a tightening of the airways |
| -stenosis | narrowing | arteriostenosis — a narrowing of an artery |
| -edema | swelling from fluid | lymphedema — swelling from lymph that cannot drain |
Procedures, records and specialists
| Suffix | Means | Word, and what it means |
|---|---|---|
| -scopy | viewing with an instrument | endoscopy — viewing the inside of a tract |
| -ectomy | surgical removal | appendectomy — removal of the appendix |
| -otomy | a cutting into | tracheotomy — a cutting into the windpipe |
| -ostomy | a surgical opening | colostomy — an opening from the colon to the surface |
| -plasty | repair, reshaping | angioplasty — repair of a blood vessel |
| -rrhaphy | suturing | herniorrhaphy — suturing a hernia |
| -centesis | a puncture to draw fluid | amniocentesis — sampling amniotic fluid |
| -gram | a record or image | electrocardiogram — a record of the heart's electrical activity |
| -graphy | the process of recording | radiography — imaging with radiation |
| -meter | an instrument for measuring | spirometer — an instrument that measures lung volumes |
| -logy | the study of | hematology — the study of blood |
| -logist | a specialist in | oncologist — a specialist in cancer care |
| -algia | pain | arthralgia — joint pain |
| -ic, -al, -ary | relating to | cardiac, renal, pulmonary — relating to the heart, kidney, lungs |
| -ous | full of, having | mucous — producing mucus |
Two pairs are easy to mix and worth naming. -ectomy removes, -otomy cuts into, -ostomy makes a new opening that stays; the three words differ in what happens to the tissue afterwards. -gram is the record, -graph is the instrument that makes it, -graphy is the process — a cardiogram is the tracing, a cardiograph is the machine.
Plurals: the endings that do not take an s
Medical words keep the plural of the language they were borrowed from, so the plural is learned with the word itself. The pattern is regular once you know it.
| Singular ending | Plural ending | Example |
|---|---|---|
| -a | -ae | vertebra → vertebrae |
| -us | -i | bronchus → bronchi; stimulus → stimuli |
| -um | -a | bacterium → bacteria; atrium → atria |
| -on | -a | criterion → criteria |
| -is | -es | diagnosis → diagnoses; crisis → crises |
| -ix, -ex | -ices | appendix → appendices; cortex → cortices |
The rule of thumb: if the word ends in -is, the plural is -es and the vowel changes; if it ends in -um, the plural is -a. The plural of analysis is analyses, not analysises, and the plural of datum is data, which is why "the data show" is correct in careful writing even though "the data shows" is common in speech.
Confusable pairs: the words that cost the easiest point
These are pairs a question can test without any medical content at all, and a passage can turn on one of them. The right-hand column is the test that separates them; Grammar takes the usage rules further.
| Pair | The distinction | The test |
|---|---|---|
| affect / effect | affect is usually a verb (to influence); effect is usually a noun (a result) | if you can put "the" in front of it, it is effect |
| advice / advise | advice is the noun; advise is the verb | "she gave me ___" takes the noun |
| breath / breathe | breath is the noun; breathe is the verb | "to ___" takes the verb |
| accept / except | accept means to receive; except means to leave out | "everyone ___ one" needs except |
| conscious / conscience | conscious means awake or aware; conscience is the sense of right and wrong | "the patient was ___" (awake) takes conscious; "a guilty ___" takes conscience |
| complement / compliment | complement completes; compliment praises | a full set complements; a nice remark compliments |
| discreet / discrete | discreet means tactful; discrete means separate | separate items are discrete |
| elicit / illicit | elicit means to draw out; illicit means unlawful | a response is elicited |
| eminent / imminent | eminent means distinguished; imminent means about to happen | a risk that is about to happen is imminent |
| ensure / insure | ensure means to make certain; insure means to cover by insurance | "___ that the door is locked" takes ensure |
| loose / lose | loose means not tight; lose means to no longer have | "did not ___ the chart" takes lose |
| precede / proceed | precede means to come before; proceed means to go on | the step that comes first precedes |
| principal / principle | principal means main, or a leading person; principle is a rule or belief | "the ___ reason" takes principal |
| stationary / stationery | stationary means not moving; stationery is paper and envelopes | a patient who does not move is stationary |
| than / then | than compares; then marks time | a comparison takes than |
| their / there / they're | possession / place / "they are" | substitute "they are" and see if the sentence survives |
The general words a passage uses
These are the words that carry a passage's argument rather than its subject. Each is defined in one line and used in a sentence this course wrote.
| Word | Means | In a sentence |
|---|---|---|
| acute | sharp, severe, or of short duration | The acute pain subsided within an hour of the dose. |
| adequate | enough for the purpose | An adequate supply of gloves was kept at every station. |
| adverse | harmful, unfavorable | The adverse reaction was reported the same day. |
| ambiguous | open to more than one reading | The order was ambiguous, so the nurse repeated it back. |
| chronic | long-lasting, persisting | Chronic conditions need review at every visit. |
| compensate | to make up for a loss or a defect | The body compensates for the blood loss by narrowing vessels. |
| comply | to act in line with a rule or request | The unit complied with the new hand-hygiene policy. |
| concur | to agree | The second clinician would concur with the diagnosis once the scan was read. |
| consequence | a result that follows | A consequence of the delay was a longer stay. |
| consistent | the same each time, without contradiction | Her notes were consistent across all three visits. |
| deteriorate | to become worse | The patient's breathing deteriorated overnight. |
| distinguish | to tell one thing from another | Distinguish a faint pulse from no pulse before starting compressions. |
| exacerbate | to make worse | Cold air exacerbates the cough. |
| facilitate | to make easier | A checklist facilitates the handover between shifts. |
| imply | to suggest without stating | The note implies the dressing was changed, but does not say so. |
| infer | to conclude from evidence | From the chart you can infer that the dose was doubled. |
| minimal | the least possible in the circumstances | Movement was kept to a minimal level. |
| monitor | to watch over time | Monitor the site for redness every four hours. |
| predispose | to make more likely in advance | A long stay predisposes a patient to weakness. |
| prevalent | common in a place or group | The condition is more prevalent in older adults. |
| prohibit | to forbid | The policy prohibits reusing a single-use needle. |
| reluctant | unwilling | The patient was reluctant to describe the pain. |
| residual | what remains | A residual cough persisted for a week. |
| subsequent | coming after | A subsequent test confirmed the first result. |
| sufficient | enough | Sufficient fluid intake was recorded on the chart. |
| symptomatic | showing signs of a condition | She remained symptomatic for two days. |
| tolerate | to endure without serious harm | He tolerated the medication without nausea. |
| unremarkable | within normal limits | The abdominal exam was unremarkable. |
| vital | necessary to life, or essential | Vital signs were recorded on admission. |
| withhold | to hold back deliberately | The dose was withheld until the blood pressure was checked. |
The health-care terms a passage assumes you know
These are terms a reading passage may use without defining, because the writer expects a health-care student to have met them. The definition is the plain meaning; the sentence is ours.
| Term | Means | In a sentence |
|---|---|---|
| afebrile | without fever | The child was afebrile by the second morning. |
| ambulatory | able to walk; not bed-bound | The patient was ambulatory by the third day. |
| bolus | a single dose given at once; also a mass of chewed food ready to swallow | The bolus was given over two minutes. |
| contusion | a bruise | A contusion spread across the forearm. |
| cyanosis | a blue-gray tint from low oxygen | Cyanosis at the lips prompted an immediate oxygen check. |
| diaphoresis | heavy sweating | Diaphoresis accompanied the drop in blood pressure. |
| distention | swelling from internal pressure | Abdominal distention was noted after the meal. |
| dysphagia | difficulty swallowing | Dysphagia put the patient on a soft diet. |
| emesis | vomiting | Emesis followed the second dose. |
| febrile | having a fever | The patient remained febrile through the night. |
| flatus | gas passed from the bowel | Passing flatus was the sign the bowel had resumed. |
| hematemesis | vomiting blood | Hematemesis was reported to the clinician at once. |
| idiopathic | of unknown cause | The diagnosis was idiopathic, meaning no cause was found. |
| incontinence | loss of control over urine or stool | Incontinence was recorded at each check. |
| intubate | to place a tube in the airway | The team chose to intubate before the transfer. |
| laceration | a cut | The laceration was cleaned and closed. |
| lethargy | unusual drowsiness and low energy | Lethargy in an older patient is a warning sign. |
| malaise | a general feeling of being unwell | Malaise was the only symptom reported. |
| necrosis | death of tissue | Necrosis at the wound edge required review. |
| orthopnea | breathlessness when lying flat | Orthopnea led her to sleep propped up. |
| pallor | unusual paleness | Pallor and cool skin suggested poor circulation. |
| pruritus | itching | Pruritus spread across the chest and back. |
| purulent | containing pus | The drainage turned purulent by day four. |
| rales | crackling sounds heard in the lungs | Rales were heard at both bases. |
| syncope | fainting | Syncope on standing was reported twice. |
| vertigo | a sense of spinning | Vertigo made the walk to the bathroom unsafe. |
| void | to pass urine | The patient voided within an hour of surgery. |
Deriving a word that is not on this page
Most terms a passage uses are not in any list, including this one. Four steps will get you a working meaning.
- Take the suffix first. It tells you what kind of word this is: a condition (-itis, -osis), a procedure (-ectomy, -scopy), a specialist (-logist), or a description (-ic, -al).
- Find the root. It names the part or the substance. Where two roots appear, the first usually names a part and the second the thing done or found there, as in gastr-o-enter-itis — stomach and intestine, both inflamed.
- Read the prefix last. It changes direction or degree: sub- under, hyper- above, brady- slow, poly- many.
- Check the whole against the sentence. A derived meaning that contradicts the sentence is wrong, and the sentence wins. Context is the final test, not the parts.
Worked example: pericardiocentesis. Suffix -centesis — a puncture to draw fluid. Root cardi — heart. Prefix peri- — around. So: a puncture into the sac around the heart to draw off fluid. A sentence saying "the fluid was sent for culture" confirms the reading; a sentence saying the patient was given a tablet would not, and the sentence would overrule the parts.
The list, in one place
Every word part this page teaches, alphabetized, with no example word and no explanation beside it. The point of the plain version is that it can be drilled: cover the middle column, read the part, say what it does, and uncover. A part you can say cold is a part you will read correctly inside a word you have never seen; a part you can only recognize in the example word it was taught with has not been learned yet.
96 parts is not a memorization project to finish in one sitting. Three passes of ten minutes, a day apart, with the third pass done from the part alone, moves more than an hour of re-reading the tables above.
The parts are not the whole vocabulary section: a 150-word list of the words this course teaches covers the general, health-care and science terms that are used rather than dissected.
| Word part | Means | Kind |
|---|---|---|
| a-, an- | without | prefixes |
| ab- | away from | prefixes |
| abdomin- | abdomen | roots |
| ad- | toward | prefixes |
| -algia | pain | suffixes |
| ante- | before | prefixes |
| anti- | against | prefixes |
| arthr- | joint | roots |
| bi-, di- | two | prefixes |
| brady- | slow | prefixes |
| cardi- | heart | roots |
| -centesis | a puncture to draw fluid | suffixes |
| cerebr- | brain | roots |
| circum- | around | prefixes |
| col-, colon- | colon | roots |
| contra- | against | prefixes |
| cost- | rib | roots |
| cutane- | skin | roots |
| cyst- | bladder, sac | roots |
| de- | down, away from | prefixes |
| derm-, dermat- | skin | roots |
| dis- | apart, not | prefixes |
| dys- | difficult, abnormal | prefixes |
| -ectomy | surgical removal | suffixes |
| -edema | swelling from fluid | suffixes |
| -emia | a condition of the blood | suffixes |
| encephal- | brain | roots |
| endo- | within | prefixes |
| enter- | intestine | roots |
| epi- | on, over | prefixes |
| eu- | normal, good | prefixes |
| extra- | outside | prefixes |
| gastr- | stomach | roots |
| glyc- | sugar | roots |
| -gram | a record or image | suffixes |
| -graphy | the process of recording | suffixes |
| hem-, hemat- | blood | roots |
| hemi- | half | prefixes |
| hepat- | liver | roots |
| hist- | tissue | roots |
| hyper- | above normal | prefixes |
| hypo- | below normal | prefixes |
| -iasis | a condition, often caused by something | suffixes |
| -ic, -al, -ary | relating to | suffixes |
| infra- | below | prefixes |
| inter- | between | prefixes |
| intra- | inside | prefixes |
| -itis | inflammation | suffixes |
| lip- | fat | roots |
| -logist | a specialist in | suffixes |
| -logy | the study of | suffixes |
| macro- | large | prefixes |
| mal- | bad, abnormal | prefixes |
| mega- | very large | prefixes |
| -megaly | enlargement | suffixes |
| -meter | an instrument for measuring | suffixes |
| micro- | small | prefixes |
| mono-, uni- | one | prefixes |
| my-, myo- | muscle | roots |
| neo- | new | prefixes |
| nephr- | kidney | roots |
| neur- | nerve | roots |
| oligo- | few, scanty | prefixes |
| -oma | a tumor or swelling | suffixes |
| -osis | a condition, often abnormal | suffixes |
| oste- | bone | roots |
| -ostomy | a surgical opening | suffixes |
| -otomy | a cutting into | suffixes |
| -ous | full of, having | suffixes |
| -pathy | disease | suffixes |
| peri- | around | prefixes |
| -plasty | repair, reshaping | suffixes |
| -plegia | paralysis | suffixes |
| -pnea | breathing | suffixes |
| poly- | many, much | prefixes |
| post- | after | prefixes |
| pre- | before | prefixes |
| pulmon-, pneum- | lung, air | roots |
| quadri- | four | prefixes |
| ren- | kidney | roots |
| retro- | backward, behind | prefixes |
| -rrhaphy | suturing | suffixes |
| -rrhea | flow, discharge | suffixes |
| -scopy | viewing with an instrument | suffixes |
| semi- | half | prefixes |
| -spasm | an involuntary contraction | suffixes |
| -stenosis | narrowing | suffixes |
| sub- | under, below | prefixes |
| supra- | above | prefixes |
| tachy- | fast | prefixes |
| therm- | heat | roots |
| thorac- | chest | roots |
| trans- | across, through | prefixes |
| tri- | three | prefixes |
| -uria | a condition of the urine | suffixes |
| vas-, vascul- | vessel | roots |
Sort order is alphabetical on the part itself, so -algia sits among the a's regardless of the dash and -ectomy among the e's. Where two spellings mean the same thing — nephr- and ren-, mono- and uni- — they are one line, because the exam will not ask you which spelling is more correct.
The traps, collected
| The trap | What it looks like | The fix |
|---|---|---|
| Common mistake: picking the most familiar meaning | Wrong: practice read as "rehearse" in a clinical passage | substitute the choice back into the sentence |
| Common mistake: ignoring the part of speech | Wrong: effect chosen where the sentence needs a verb | decide which word class the blank needs first |
| Common mistake: reading half the prefix | Wrong: hypo- read as hyper- | read the prefix to its last letter; they mean opposites |
| Common mistake: taking a word part out of order | Wrong: the -ia of bradycardia read as the a- of apnea, so the last piece is taken for the first and the root is skipped | read suffix back to prefix: brady- (slow) + cardi (heart) + -ia (condition) |
| Common mistake: trusting a near-synonym | a choice that is close but shifts the degree | ask whether the sentence says "a lot" or "a little" |
| Common mistake: assuming one spelling per root | Wrong: nephr- missed because the word says renal | learn the root pairs, not single spellings |
| Common mistake: dropping the combining vowel wrongly | Wrong: gastritis read as gastr-o-itis | the vowel is dropped before a vowel-initial suffix |
| Common mistake: choosing a true statement that does not answer | the choice defines the word but not its sense here | answer the sentence's question, not the dictionary's |
How to practice this
- Build ten words a day from parts. Take a suffix from this page and a root, add a prefix, and write the meaning before you look it up. Ten a day is seventy a week, and the same parts come round again.
- Keep a context notebook. When a word stops you, write the sentence down, not just the word. The sentence is what you will recognize next time.
- Drill the pairs aloud. Affect and effect are separated by a frame rather than a definition: say "the effect" and "to affect" until the frame is automatic.
- Read one label a day. A medication label or an instruction sheet gives you real sentences with real terms, and the same terms appear on the next label.
- Test yourself backwards. Given a meaning, produce the word. Recognition is what a passage question asks for, but producing the word is what proves you know it.
Where to go next
- The subject's own page — Vocabulary lists what is published for this subject, including its guide and its practice set as they land.
- The sentences these words sit in — Grammar: agreement, punctuation and the errors that make a clear word ambiguous.
- Reading a passage that uses them — Reading Comprehension: the method for finding the one line that answers a question.
- The science behind the roots — Biology and Chemistry: the body systems and the substances these terms name.
Sources. The prefix, root and suffix lists follow the US National Library of Medicine's
consumer guidance on understanding medical words (medlineplus.gov), US federal government
material that is not subject to copyright in the United States; the word parts and their
meanings are standard medical terminology and are given here in our own words. The plural
patterns follow the same guidance and standard English usage. Every definition, example
sentence and table on this page was written for this course; no dictionary or glossary text is
reproduced. The publisher's own account of the areas the exam covers is quoted from its HESI A2
page. Accessed 2026-10-27.
HESI A2 is a trademark of Elsevier Inc. Elk Ridge Academy is an independent study resource and is not affiliated with, endorsed by, or sponsored by Elsevier Inc. Exam names are used descriptively only.
Source: MedlinePlus (US National Library of Medicine) consumer guidance on understanding medical words for the prefix, root and suffix system and for plural patterns. US federal government material, not subject to copyright in the United States. Every definition, example sentence and table is written for this course (MedlinePlus accessed 2026-10-27; the Elsevier HESI A2 page accessed 2026-10-23)