Glossary
pericardium
The pericardium is the sac around the heart — a fibrous outer layer and a fluid-filled inner space that lets it beat without friction.
The pericardium is the sac that encloses the heart. Its outer layer is tough fibrous tissue that anchors the heart in the chest and resists overfilling; its inner, serous layer folds into two, one pressed against the heart itself and one lining the fibrous sac, with a thin film of fluid between them. The fluid is why a heart beating tens of millions of times a year does not wear itself out against its own container — the surfaces slide. The sac has a limit, which is the clinical point: fluid that accumulates slowly stretches it, but fluid that arrives fast has nowhere to go, and the pressure inside then squeezes the chambers so that they cannot fill. Because the pericardium is fused to the diaphragm below, the heart moves with breathing, a small detail that shows up on an image.
Taught in
Related terms
- pleura — The pleura is the double membrane around each lung — one layer on the lung, one on the chest wall, with a thin film of fluid between them.
Source: The anatomy and physiology guide in this course, whose organ and tissue descriptions follow the US National Cancer Institute's SEER Training Modules and MedlinePlus consumer health pages. Both are US federal government material, not subject to copyright in the United States. The definition above is written for this course in our own words. (SEER Training Modules accessed 2026-10-26; definition written 2026-10-27)